Melanotan 1 (10MG) Analytical Reference Material (In Vitro Research Only)
Melanotan 1 (afamelanotide) is a synthetic 13-amino-acid analog of alpha-MSH, the natural hormone that signals through melanocortin receptors in pigment cells. Two amino-acid substitutions make it more resistant to enzymatic breakdown, which a 1980 biochemistry study linked to prolonged activation of the MC1R receptor.
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1:1 Analytical & Chemical Specifications
| Analytical Parameter | Verified Specification |
|---|---|
| CAS Number | 75921-69-6 |
| Molecular Formula | C78H111N21O19 |
| Molecular Weight | 1646.85 g/mol (Da) |
| Amino Acid Sequence | Ac-Ser-Tyr-Ser-Nle-Glu-His-D-Phe-Arg-Trp-Gly-Lys-Pro-Val-NH2 (Afamelanotide, 13 AA) |
| Chromatographic Purity (RP-HPLC) | >=99.0% Peak Area (Observed Lot 2026MELAN10A: 99.3%) |
| Identity Verification | Electrospray Ionization Mass Spectrometry (ESI-MS) |
| Physical Form | Lyophilized Powder in Sealed Desiccated Glass Vial |
| Recommended Storage | -20°C Desiccated & Protected from Light |
| Regulatory Classification | Research Use Only (RUO) — Not a 503A Compounding Pharmacy Product; Strictly Not for Human or Veterinary Use |
| Lot Traceability | Lot 2026MELAN10A (Tested 2026-02-05) — Verify Dataset in COA Library → |
Lot-Specific Certificate of Analysis (COA)
In Vitro Laboratory Research Scope
Typical laboratory uses: MC1R receptor-binding assays, melanin (eumelanin) synthesis pathways in melanocyte cultures, and enzymatic-stability comparisons with native alpha-MSH. For in-vitro laboratory research only. Not for human or animal use.
Analytical Verification & Storage Parameters for Melanotan 1
How is the chromatographic purity of Melanotan 1 (10MG) verified?
Every production batch of Melanotan 1 (10MG), including active Lot 2026MELAN10A, undergoes independent Reverse-Phase High-Performance Liquid Chromatography (RP-HPLC) with UV/Vis detection at 214 nm and Electrospray Ionization Mass Spectrometry (ESI-MS), confirming 99.3% peak area purity (retention time 10.18 min) and exact molecular mass concordance prior to catalog release.
What are the laboratory storage and stability parameters for lyophilized Melanotan 1?
Lyophilized Melanotan 1 reference material is supplied in a sealed, desiccated borosilicate glass vial under inert atmosphere and must be stored at -20°C protected from light to prevent hydrolytic or oxidative cleavage. Once solubilized in sterile aqueous buffer for in vitro assays, maintain aliquots at 2°C to 8°C and avoid repeated freeze-thaw cycles.
What are the chemical identifiers and regulatory classification of Melanotan 1?
Melanotan 1 is characterized by CAS Registry identifier 75921-69-6, molecular formula C78H111N21O19, and theoretical molecular weight 1646.85 g/mol (Da). Regenerative Health Peptides supplies this reagent strictly as a Research Use Only (RUO) analytical reference material for qualified 21+ in vitro laboratory investigations, never for human or veterinary use.
Primary Scientific Literature & Preclinical Citations
Peer-ReviewedThe following peer-reviewed scientific publications report preclinical investigations into the biochemical mechanisms and receptor pharmacology of this compound. Regenerative Health Peptides supplies this material strictly for in-vitro laboratory research.
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