Tesamorelin 10mg

$117.00

Tesamorelin 10mg is a synthetic growth hormone-releasing peptide (GHRP) that stimulates the pituitary gland to produce growth hormone. Tested for purity, ID and Labelled by Regenerative Health Peptides in the USA, this research-grade peptide is offered exclusively for in-vitro studies. Ideal for researchers investigating muscle growth, fat loss, and weight loss metabolism, Tesamorelin is not intended for human or animal use.

Category:

Overview

Tesamorelin is a growth hormone-releasing hormone (GHRH) analog that works by stimulating the pituitary gland to release growth hormone. Tesamorelin enhances fat metabolism, facilitates muscle growth, and promotes overall weight loss by increasing the secretion of growth hormone. Unlike direct growth hormone injections, Tesamorelin stimulates the body’s natural production of growth hormone, providing a more physiological response for researchers studying metabolic disorders, body composition, and musculoskeletal regeneration.

Molecular Characteristics

Property Data
Sequence Ser-Ala-Ser-Ala-Ser-Glu-Asp-Ser-Gly-Val-Gly-Leu
Molecular Weight 1411.6 g/mol
CAS Number 616204-22-6
PubChem CID 11609475
Synonyms GH-RH-44, GH-Releasing Peptide-6

Mechanisms of Action

Tesamorelin binds to the growth hormone-releasing hormone receptor (GHRHR) in the anterior pituitary gland, triggering the release of growth hormone. This leads to increased lipolysis (fat breakdown), enhanced muscle regeneration, and overall anabolic activity. By stimulating growth hormone production, Tesamorelin also plays a role in collagen synthesis, skin regeneration, and bone density maintenance, making it a valuable peptide for anti-aging and musculoskeletal research.

Research Areas

  1. Fat Loss & Metabolic RegulationTesamorelin has been studied for its ability to increase fat metabolism, promote fat loss, and regulate lipid distribution in weight management studies.[1][2]
  2. Muscle Growth & RecoveryTesamorelin stimulates growth hormone release, supporting muscle regeneration and hypertrophy. Research indicates its role in muscle recovery after strenuous exercise and tissue repair.[3][4]
  3. Anti-Aging & Skin Regeneration – By increasing growth hormone levels, Tesamorelin promotes collagen production and skin elasticity, making it a target for anti-aging studies.[5][6]
  4. Bone Health & OsteoporosisTesamorelin plays a role in bone mineralization and density, showing promise in osteoporosis and bone health research.[7][8]
  5. Endocrine & Hormonal Regulation – As a growth hormone secretagogue, Tesamorelin is useful in endocrine research, particularly for studying hormonal balance, testosterone levels, and muscle-wasting conditions.[9][10]

Product Usage

Tesamorelin 10mg is supplied for Research Use Only and is not intended for human or animal use. It is suitable exclusively for in-vitro studies (in glass). It has not been evaluated by the FDA for therapeutic purposes, and researchers should adhere to local regulations for safe handling and disposal.

Disclaimer


All compounds and information provided by Regenerative Health Peptides are intended solely for research and educational purposes. These materials are not medicines, foods, or dietary supplements and must not be introduced into humans or animals. They are supplied exclusively for in-vitro laboratory studies; any other use is strictly prohibited by law. None of these products have been evaluated or approved by the FDA to diagnose, treat, cure, or prevent any disease.

2.1 Fat Loss & Metabolic Regulation

Tesamorelin has demonstrated significant effects on fat loss by stimulating growth hormone secretion. It is used in research to understand its ability to reduce visceral fat and improve lipid metabolism in animal models of obesity and metabolic syndrome. Studies have shown that Tesamorelin can increase fat oxidation, promote lipolysis, and enhance fat loss without the need for exercise, making it an effective compound for weight loss and fat reduction research.[11][12]

  • By regulating insulin sensitivity and improving lipid profiles, Tesamorelin has been evaluated for its potential to treat obesity and improve metabolic health in preclinical models of fat accumulation.[13][14]

2.2 Muscle Growth & Recovery

Tesamorelin has been studied for its effects on muscle growth, muscle regeneration, and tissue repair. Research indicates that Tesamorelin stimulates growth hormone release, which enhances protein synthesis, muscle hypertrophy, and muscle recovery. By promoting muscle regeneration and collagen production, Tesamorelin aids in tissue repair after musculoskeletal injuries and during post-exercise recovery.[15][16]

  • Studies show that Tesamorelin can be effective in preventing muscle wasting and atrophy associated with aging or disease, making it a key peptide in muscle regeneration research.[17]

2.3 Anti-Aging & Skin Regeneration

As an indirect stimulator of growth hormone, Tesamorelin is frequently studied for its anti-aging effects. By increasing collagen synthesis and enhancing skin elasticity, Tesamorelin can improve skin health, reduce wrinkles, and provide photo-protection. It is used in anti-aging studies to explore its potential to reverse skin aging and photo-aging induced by UV exposure.[18][19]

  • Its ability to stimulate growth hormone also supports bone density and skin regeneration, contributing to overall anti-aging therapies.[20]

2.4 Bone Health & Osteoporosis

The effect of Tesamorelin on bone health has been explored in the context of osteoporosis and bone mineralization. Tesamorelin has shown promise in bone density studies, helping to maintain or increase bone mass in aging individuals or those with growth hormone deficiency. Research indicates that Tesamorelin could play a role in osteoporosis treatments and bone health improvement.[21][22]

  • It also helps in bone regeneration, providing an additional benefit in bone fracture healing studies.[23]

2.5 Endocrine & Hormonal Regulation

As a growth hormone secretagogue, Tesamorelin stimulates the pituitary gland to release growth hormone, affecting hormonal balance and overall endocrine function. Research indicates its ability to enhance testosterone levels, improve muscle mass, and promote anabolic processes, making it valuable in endocrine research and hormonal therapy.[24][25]

  • Tesamorelin is used to study growth hormone deficiency and its effects on aging and muscle regeneration.

Reference List 

  1. Chavez et al., FASEB Journal 32, 2120–2130 (2018)
  2. Lin et al., Clinical Nutrition 36, 241–247 (2017)
  3. Gray et al., Endocrinology 156, 319–331 (2015)
  4. Smith et al., Obesity 23, 231–245 (2015)
  5. Wang et al., Molecular Endocrinology 31, 615–628 (2017)
  6. Mason et al., Journal of Clinical Investigation 128, 3832–3840 (2018)
  7. Nakamura et al., Endocrinology 162, 45–56 (2017)
  8. Markus et al., Journal of Gerontology 63, 87–95 (2017)
  9. Chang et al., Journal of Endocrinology 226, 123–132 (2019)
  10. Hernandez et al., Journal of Bone and Mineral Research 30, 431–439 (2016)
  11. Berglund et al., Journal of Clinical Endocrinology and Metabolism 102, 1180–1188 (2017)
  12. Fitzpatrick et al., Journal of Clinical Nutrition 92, 492–499 (2016)
  13. Jones et al., Journal of Clinical Investigation 127, 2965–2974 (2017)
  14. Chang et al., Journal of Obesity 2018, 2148650 (2018)
  15. Chavez et al., Journal of Clinical Endocrinology and Metabolism 103, 3968–3977 (2018)
  16. Carver et al., Hormone and Metabolic Research 47, 473–480 (2015)
  17. Thompson et al., J Clinical Investigation 130, 2124–2133 (2020)
  18. Brown et al., American Journal of Physiology 305, E1134–E1140 (2013)
  19. Sharma et al., Regenerative Medicine 11, 223–234 (2016)
  20. Taylor et al., Obesity Reviews 19, 22–35 (2018)
  21. Harrison et al., Journal of Clinical Endocrinology and Metabolism 100, 3192–3198 (2015)
  22. Mason et al., Journal of Aging Research 2020, 21654 (2020)
  23. Gioffre et al., Clinical Nutrition 34, 1522–1531 (2015)
  24. Lopez et al., Journal of Muscle Research and Cell Motility 38, 395–409 (2017)
  25. Sharma et al., Obesity Reviews 21, 267–276 (2020)
  • Lyophilized / Dry powder: Store at -20 °C (dark, desiccated); shelf life ~12 months.
  • Dissolved (aqueous): sterile water, 4 °C, use within 7 days.
  • Long-term: aliquot & -80 °C for up to 6 months; avoid > 2 freeze-thaw cycles.