SS-31 10mg

SS-31 10mg

SS-31 10mg

$83.00

SS-31 10mg, also known as Elamipretide or Bendavia, is a peptide that targets mitochondrial dysfunction and oxidative stress. All our research peptides are tested for purity, ID and Labelled under strict standards by Regenerative Health Peptides in the USA, this research-grade peptide is exclusively for in-vitro studies. Ideal for researchers investigating mitochondrial health, cardiovascular disease, and aging pathways, SS-31 is not intended for human or animal use.

Category:

Overview

SS-31, also known as Elamipretide or Bendavia, is a synthetic peptide designed to target mitochondrial dysfunction and oxidative stress. It has been extensively studied for its potential in cardiovascular research, aging, and neurological conditions. By targeting mitochondria, SS-31 helps in improving mitochondrial membrane potential and reducing oxidative damage, which plays a key role in cellular health. This peptide is increasingly important in aging studies, mitochondrial diseases, and heart health.

Molecular Characteristics

Property Data
Sequence H-D-Arg-Ser-Asp-Tyr-Lys-Pro-Asp-Glu-Glu-Tyr-NH2
Molecular Weight 1191.4 g/mol
CAS Number 329603-41-8
PubChem CID 6075431
Synonyms Elamipretide, Bendavia, SS-31

Mechanisms of Action

SS-31 works by selectively targeting mitochondria, the powerhouses of the cell, and stabilizing the mitochondrial membrane. It also protects mitochondria from oxidative stress, which is known to be a significant factor in aging, neurodegeneration, and cardiovascular diseases. SS-31 is believed to enhance mitochondrial function and improve ATP production, contributing to increased cellular energy and improved cellular health.

Research Areas

  1. Mitochondrial Health & Aging – SS-31 has been shown to support mitochondrial function and bioenergetics by reducing reactive oxygen species (ROS) and stabilizing mitochondrial membranes, making it vital for aging and age-related diseases.[1][2]
  2. Cardiovascular Disease – Research has demonstrated that SS-31 has potential as a cardioprotective peptide, improving cardiac function and reducing ischemic damage in preclinical models of heart disease.[3][4]
  3. Neurological Research – SS-31 is explored for its potential in neuroprotection and mitochondrial rescue in neurodegenerative diseases like Alzheimer’s and Parkinson’s disease.[5][6]
  4. Muscle Regeneration & Repair – SS-31 has been shown to help improve muscle recovery, increase muscle strength, and support muscle regeneration in research settings focused on skeletal muscle health.[7][8]
  5. Cellular Health & Oxidative Stress – SS-31 targets oxidative stress, which is associated with mitochondrial dysfunction, aging, and disease pathogenesis. Research suggests it could be beneficial in treating chronic inflammatory diseases and improving cellular resilience.[9][10]

Product Usage

SS-31 10mg is supplied for Research Use Only and is not intended for human or animal use. It is suitable exclusively for in-vitro studies (in glass) and has not been evaluated by the FDA for therapeutic purposes. Researchers must comply with all local regulations when handling this peptide.

Disclaimer


All compounds and information provided by Regenerative Health Peptides are intended solely for research and educational purposes. These materials are not medicines, foods, or dietary supplements and must not be introduced into humans or animals. They are supplied exclusively for in-vitro laboratory studies; any other use is strictly prohibited by law. None of these products have been evaluated or approved by the FDA to diagnose, treat, cure, or prevent any disease.

2.1 Mitochondrial Health & Aging

SS-31 has been widely studied for its effects on mitochondrial health and its potential to extend lifespan. By stabilizing mitochondrial membranes and reducing ROS production, SS-31 helps maintain mitochondrial integrity and prevents damage from oxidative stress, which is linked to aging and age-related diseases. Studies indicate that SS-31 can reduce the markers of aging by improving mitochondrial function and enhancing ATP production.[11][12]

  • Research in aging models has shown that SS-31 can increase lifespan and improve overall cellular health in various organ systems, making it an important peptide in anti-aging research.

2.2 Cardiovascular Health

SS-31 has been shown to have cardioprotective effects by improving mitochondrial function and protecting the heart from ischemic injury. In preclinical models, SS-31 has been studied for its ability to reduce myocardial infarction damage and improve cardiac function. The peptide enhances ATP production in the heart, improving energy balance and function, which is crucial in cardiovascular disease research.[13][14]

  • SS-31 may also improve vascular health by reducing oxidative stress and enhancing vascular endothelial function, making it a promising peptide for vascular research and cardiac rehabilitation.

2.3 Neuroprotection & Neurological Diseases

The ability of SS-31 to reduce oxidative stress and improve mitochondrial function makes it a promising candidate for neuroprotection. In animal models of Parkinson’s disease and Alzheimer’s, SS-31 has shown potential in preventing neuronal death, improving synaptic plasticity, and enhancing neurogenesis. SS-31 has also been linked to reduced neuroinflammation, suggesting it could be useful in treating neurodegenerative diseases.[15][16]

  • Its neuroprotective properties make it an excellent focus for neurodegenerative research and potential therapies for diseases like Parkinson’s and Alzheimer’s.

2.4 Muscle Regeneration & Repair

Research has indicated that SS-31 can enhance muscle regeneration and improve muscle recovery after injury. By improving mitochondrial function and oxidative stress reduction, SS-31 aids in muscle tissue repair and recovery following musculoskeletal injuries. Studies also suggest that SS-31 enhances muscle strength and helps in post-exercise recovery, making it an important peptide for muscle health and rehabilitation research.[17][18]

  • Its ability to promote muscle regeneration also links it to anti-aging treatments by improving muscle function in older individuals.

2.5 Oxidative Stress & Inflammatory Diseases

The ability of SS-31 to reduce oxidative stress is crucial in the context of inflammatory diseases. By stabilizing mitochondria and reducing ROS, SS-31 can help prevent the progression of chronic inflammatory diseases, such as rheumatoid arthritis and inflammatory bowel disease (IBD). Studies have shown that SS-31 could help reduce systemic inflammation and support the body’s natural healing response.[19][20]

  • Research suggests that SS-31 could be an effective tool in treating inflammatory conditions by reducing oxidative damage at the cellular level.

Reference List 

  1. Sharma et al., Mitochondrial Function and Longevity 4, 171–178 (2019)
  2. Bergman et al., FASEB Journal 32, 1405–1416 (2018)
  3. Johnson et al., Journal of Clinical Endocrinology 101, 2451–2461 (2019)
  4. Martin et al., Journal of Clinical Investigation 128, 497–509 (2018)
  5. Nguyen et al., Biochemical Pharmacology 118, 65–73 (2016)
  6. Fang et al., Cell Metabolism 28, 659–672 (2018)
  7. Zhao et al., Nature Medicine 24, 392–403 (2018)
  8. Girotti et al., Journal of Neurochemistry 146, 1324–1335 (2017)
  9. Liu et al., Free Radical Biology and Medicine 130, 120–128 (2018)
  10. Kumar et al., Journal of Clinical Investigation 128, 340–354 (2020)
  11. Perez et al., Biomaterials 31, 872–881 (2019)
  12. Schenk et al., Journal of Cardiovascular Pharmacology 61, 232–242 (2018)
  13. Vasquez et al., Molecular Therapy 23, 1234–1246 (2020)
  14. Zhu et al., Molecular Medicine 24, 71–84 (2019)
  15. Park et al., Stem Cells Translational Medicine 8, 992–1001 (2019)
  16. Parker et al., J Cell Physiol 234, 3872–3881 (2020)
  17. Kim et al., Endocrine Reviews 41, 131–145 (2020)
  18. Parker et al., Journal of Aging Research 2020, 935946 (2020)
  19. Harris et al., Journal of Immunology 199, 21–34 (2017)
  20. Thompson et al., Free Radical Biology and Medicine 154, 56–70 (2020)
  • Lyophilized / Dry powder: Store at -20 °C (dark, desiccated); shelf life ~12 months.
  • Dissolved (aqueous): sterile water, 4 °C, use within 7 days.
  • Long-term: aliquot & -80 °C for up to 6 months; avoid > 2 freeze-thaw cycles.