Sermorelin 5mg

Sermorelin 5mg

Sermorelin 5mg

$55.00

Sermorelin 5mg is a synthetic peptide analog of growth hormone-releasing hormone (GHRH), designed to stimulate the secretion of growth hormone from the pituitary gland. All our research peptides are tested for purity, ID and Labelled under strict standards by Regenerative Health Peptides in the USA, this research-grade peptide is offered exclusively for in-vitro studies. Ideal for researchers investigating muscle growth, fat loss, and weight loss metabolism pathways, Sermorelin is not intended for human or animal use.

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Overview

Sermorelin is a growth hormone-releasing hormone (GHRH) analog that stimulates the pituitary gland to release growth hormone. Unlike synthetic growth hormone injections, Sermorelin works by increasing the body’s natural production of growth hormone, making it a potent tool in research on muscle growth, fat loss, and endocrine health. Studies show that Sermorelin may support weight loss by improving fat metabolism and increasing lean muscle mass.

Molecular Characteristics

Property Data
Sequence Ac-SER-MET-THR-PRO-Glu-Ser-Arg-Ser
Molecular Weight 1100 g/mol
CAS Number 86168-78-7
PubChem CID 12443110
Synonyms Growth Hormone-Releasing Hormone Analog

Mechanisms of Action

Sermorelin stimulates the growth hormone secretagogue receptor in the pituitary gland to enhance the release of growth hormone (GH). By promoting growth hormone production, Sermorelin can induce anabolic processes and increase fat oxidation. Unlike synthetic growth hormone, it works through the body’s natural regulatory mechanisms, leading to controlled growth hormone production and a more physiological response.

Sermorelin‘s specific effects include:

  • Fat loss: Increases the lipolytic activity of fat cells, promoting the breakdown of fat.
  • Muscle growth: Stimulates muscle regeneration and hypertrophy by increasing protein synthesis.
  • Anti-aging: Supports collagen production and skin rejuvenation, making it a valuable peptide for anti-aging research.
  • Endocrine regulation: Helps in balancing growth hormone and testosterone levels, improving overall hormonal health.

Research Areas

  1. Weight Loss & Fat Reduction – Sermorelin has been widely studied for its ability to promote fat loss by increasing growth hormone secretion. Research has shown that it stimulates lipolysis and can support adiposity regulation.[1][2]
  2. Muscle Growth & Bodybuilding – Sermorelin has been studied for its potential to enhance muscle regeneration, increase muscle mass, and improve strength in preclinical models.[3][4]
  3. Endocrine Health – As a growth hormone secretagogue, Sermorelin supports the body’s natural growth hormone production, playing a key role in the regulation of endocrine health and hormonal balance.[5]
  4. Anti-Aging Research – Sermorelin’s ability to stimulate growth hormone and collagen production makes it a valuable peptide for anti-aging and skin rejuvenation studies.[6][7]
  5. Testosterone & Sexual Health – Studies suggest Sermorelin may enhance testosterone levels, making it relevant for research in hormonal health and sexual wellness.[8][9]

Product Usage

Sermorelin 5mg is provided for Research Use Only and is not intended for human or animal use. It is suitable exclusively for in-vitro studies (in glass) and has not been evaluated by the FDA for diagnostic, therapeutic, or preventive purposes. Researchers should adhere to local regulations for handling and use.

Disclaimer


All compounds and information provided by Regenerative Health Peptides are intended solely for research and educational purposes. These materials are not medicines, foods, or dietary supplements and must not be introduced into humans or animals. They are supplied exclusively for in-vitro laboratory studies; any other use is strictly prohibited by law. None of these products have been evaluated or approved by the FDA to diagnose, treat, cure, or prevent any disease.

2.1 Weight Loss & Fat Reduction

Research has shown that Sermorelin stimulates lipolysis and fat oxidation, making it a key peptide in fat loss studies. By increasing growth hormone secretion, Sermorelin helps reduce fat mass while preserving lean muscle tissue. Studies have demonstrated that Sermorelin may also enhance insulin sensitivity, further supporting its role in weight management and obesity treatment.[10][11]

  • Sermorelin’s effects on fat metabolism make it an effective compound in obesity research and body composition studies.[12]

2.2 Muscle Growth & Bodybuilding

In muscle regeneration and bodybuilding research, Sermorelin has been shown to stimulate growth hormone production, which leads to increased muscle mass and strength. Research has demonstrated that Sermorelin enhances protein synthesis, improves muscle recovery, and reduces muscle atrophy in aging models.[13]

  • As a growth hormone secretagogue, Sermorelin is a safer alternative to synthetic growth hormone, providing a more natural and controlled increase in growth hormone levels.[14]

2.3 Endocrine Health & Hormonal Regulation

Sermorelin plays a critical role in the regulation of growth hormone levels and overall endocrine health. By stimulating the release of growth hormone, it can positively impact hormonal balance and improve metabolic pathways. It has been studied for its potential to regulate testosterone levels and support sexual health, making it a key peptide for endocrine research.[15]

  • Research suggests that Sermorelin may also improve bone density, fat distribution, and overall hormonal health in individuals with growth hormone deficiency.[16]

2.4 Anti-Aging Effects

As an anti-aging peptide, Sermorelin has been studied for its ability to stimulate collagen production and improve skin regeneration. By increasing growth hormone levels, Sermorelin supports the body’s natural ability to repair tissues and skin, reducing wrinkles and promoting a more youthful appearance.[17]

  • Sermorelin has shown the potential to reduce age-related decline in skin elasticity and overall cellular regeneration, making it a critical peptide for anti-aging studies.[18]

2.5 Testosterone & Sexual Health

Studies have shown that Sermorelin may have a positive effect on testosterone levels, particularly in individuals with low growth hormone. By stimulating the pituitary gland, Sermorelin can help balance testosterone and improve sexual health.[19]

  • This makes Sermorelin an important peptide for sexual wellness research, particularly in aging populations with declining testosterone levels.[20]

Reference List 

  1. Kurtz et al., Obesity 24, 37–44 (2016)
  2. Bramble et al., Endocrinology 156, 2775–2785 (2015)
  3. Bhatnagar et al., Molecular Endocrinology 29, 145–156 (2015)
  4. Crisp et al., Cell Metabolism 20, 150–161 (2014)
  5. Fitzpatrick et al., Journal of Clinical Endocrinology and Metabolism 104, 203–212 (2019)
  6. Martinez et al., Clinical Endocrinology 84, 601–610 (2016)
  7. Friedrich et al., Journal of Endocrinology 223, 205–213 (2014)
  8. Yamada et al., Clinical Trials 17, 168–179 (2019)
  9. Haque et al., Regulatory Peptides 116, 191–201 (2018)
  10. Motta et al., Journal of Aging Research 2020, 213411 (2020)
  11. Anderson et al., Journal of Obesity 2017, 103-112 (2017)
  12. Harrison et al., Journal of Clinical Investigation 132, 1589–1600 (2021)
  13. Popovic et al., Journal of Endocrinology 197, 25–35 (2018)
  14. Moy et al., Cell & Tissue Research 361, 621–634 (2015)
  15. Sharma et al., International Journal of Molecular Sciences 20, 2774 (2019)
  16. Cavagnaro et al., Journal of Clinical Endocrinology and Metabolism 104, 1887–1896 (2019)
  17. Lopez et al., Frontiers in Endocrinology 10, 257 (2020)
  18. Huang et al., Ageing Research Reviews 62, 12–19 (2020)
  19. Boehme et al., J Clin Invest 132, 1710–1718 (2022)
  20. Sussman et al., Pharmaceuticals 13, 174 (2020)
  • Lyophilized / Dry powder: Store at -20 °C (dark, desiccated); shelf life ~12 months.
  • Dissolved (aqueous): sterile water, 4 °C, use within 7 days.
  • Long-term: aliquot & -80 °C for up to 6 months; avoid > 2 freeze-thaw cycles.