BPC-157 + TB-500 5 mg / 5 mg

BPC-157 + TB-500 5 mg / 5 mg

BPC-157 + TB-500 5 mg / 5 mg

$10.00

BPC-157 + TB-500 5mg / 5mg is a powerful peptide blend combining BPC-157, a tissue repair peptide, with TB-500, a thymosin β4 fragment known for its regenerative properties. All our research peptides are tested for purity, ID, and labelled in the USA by Regenerative Health Peptides. This research-grade peptide combination is offered exclusively for in-vitro studies, ideal for researchers exploring musculoskeletal repair, wound healing, and angiogenesis. It is not intended for human or animal use.

Category:

Overview

BPC-157 (Body Protection Compound 157) and TB-500 (Thymosin Beta-4) are both peptides well-regarded for their regenerative properties, particularly in musculoskeletal and tissue repair studies. BPC-157 is known for its ability to accelerate wound healing, reduce inflammation, and support tendon-to-bone healing. TB-500, a fragment of the protein thymosin β4, enhances tissue repair and cell migration, while also promoting angiogenesis. When combined, these peptides have shown to be highly effective in regenerative medicine and athletic recovery research.

BPC-157 Peptide Structure

  • Sequence: Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val
  • Molecular Weight: 1419.5 g/mol
  • CAS Number: 137525-51-7
  • PubChem CID: 108101

TB-500 Peptide Structure

  • Sequence: Ac Ser Asp Lys Pro Ala Ile Glu Gln Gly Glu Ser Ile Gly Asp Lys Lys Leu Lys Glu Lys Lys Ile Gly Glu Gln Asp Lys Ser Leu Asp Lys Lys Gln Gly Glu Lys Gln Met Glu Asp Lys Ser
  • Molecular Weight: 4963.4 g/mol
  • CAS Number: 77591-33-6

Mechanisms of Action

  • BPC-157: Acts as a cytoprotective peptide with regenerative effects on muscle, tendon, and vascular tissues. It accelerates wound healing, promotes fibroblast proliferation, and enhances angiogenesis.
  • TB-500: Modulates actin dynamics, facilitating cell migration and tissue regeneration, particularly in injured muscle, ligament, and tendon tissues. It also promotes angiogenesis, aiding the formation of new blood vessels, which is vital for healing.

Together, BPC-157 and TB-500 work synergistically to accelerate muscle recovery, tendon repair, and angiogenesis—making this blend a powerful tool for research into healing processes.

Research Areas

  1. Wound Healing & Tissue Repair – The combination of BPC-157 and TB-500 has been shown to accelerate the healing of soft tissues, reduce scarring, and improve tendon and ligament repair in animal studies.[1][2]
  2. Muscle & Tendon Recovery – Research indicates that BPC-157 and TB-500 promote muscle regeneration and increased tensile strength, beneficial for studies in sports injury recovery.[3][4]
  3. Angiogenesis – Both peptides enhance vascularization, promoting blood vessel formation, which supports tissue regeneration and recovery in ischemic injury models.[5][6]
  4. Weight Loss & Metabolism – Studies suggest that BPC-157 and TB-500 may modulate metabolic processes, enhancing fat oxidation and contributing to weight loss in preclinical models.[7]
  5. Inflammation & Fibrosis – These peptides are also being studied for their anti-inflammatory properties, specifically their ability to suppress fibroblast activation and reduce fibrosis in chronic injuries.[8][9]

Product Usage

BPC-157 + TB-500 5 mg / 5 mg is supplied for Research Use Only. It is not for human or animal administration and is intended solely for in-vitro studies (in glass). This product has not been evaluated by the FDA for therapeutic, diagnostic, or preventive purposes. Researchers must follow all applicable regulations for proper handling and disposal.

Detailed Disclaimer 

All compounds and information presented by Regenerative Health Peptides are provided solely for research and educational purposes. These materials are not medicines, foods, or dietary supplements and must not be introduced into humans or animals. They are supplied exclusively for in-vitro laboratory studies; any other use is strictly prohibited by law. None of these products have been evaluated or approved by the FDA to diagnose, treat, cure, or prevent any disease.

2.1 Wound Healing & Tissue Repair

Both BPC-157 and TB-500 have been extensively researched for their regenerative properties in wound healing. BPC-157 accelerates wound closure, enhances fibroblast proliferation, and promotes collagen synthesis. Meanwhile, TB-500 plays a critical role in cell migration and vascular growth in the wound area, facilitating faster and more effective tissue repair.[10][11]

  • Combined, these peptides promote angiogenesis and collagen deposition, which is crucial for repairing muscle, ligaments, and tendons.[12][13]

2.2 Muscle & Tendon Recovery

Research on BPC-157 and TB-500 in musculoskeletal injury models has shown improved tendon-to-bone healing, ligament recovery, and muscle regeneration. Both peptides stimulate fibroblast and myoblast differentiation, which is essential for muscle repair and improving tensile strength after injury.[14][15]

  • Studies on muscle regeneration indicate that TB-500 stimulates myoblast differentiation, while BPC-157 accelerates tendon and ligament repair.[16][17]

2.3 Angiogenesis & Vascularization

BPC-157 and TB-500 both promote the formation of new blood vessels, or angiogenesis, which is essential for tissue healing and regeneration. This is particularly beneficial in the treatment of ischemic injuries and chronic wounds.[18][19]

  • Combined, they stimulate endothelial cells and promote vascular growth, making this blend an essential peptide for researchers focused on vascular health and wound healing.[20]

2.4 Weight Loss & Metabolic Effects

Emerging research on BPC-157 and TB-500 suggests potential roles in fat loss and metabolic health. These peptides may enhance fat oxidation, increase energy expenditure, and improve insulin sensitivity, making them useful for studies on weight management and obesity.[21]

  • Preclinical studies on fat loss have shown that the peptides contribute to fat mass reduction in obese models, in addition to promoting muscle regeneration and strength.[22]

2.5 Anti-Inflammatory Effects & Fibrosis Reduction

Both peptides are being investigated for their potential in reducing inflammation and fibrosis. BPC-157 has shown to suppress NF-kB inflammatory signaling, while TB-500 helps reduce the activation of fibroblasts and myofibroblasts, which are key contributors to chronic inflammation and scarring in tissues.[23][24]

  • Research also indicates that BPC-157 can reduce fibrosis in chronic injuries and prevent excessive tissue scarring.[25]

Reference List

  1. Seiwerth et al., Journal of Physiology-Paris 91, 173–178 (1997)
  2. Huang et al., Drug Design, Development and Therapy 9, 2485–2499 (2015)
  3. Šola et al., FASEB Journal 36, s1, R5345 (2022)
  4. Chang et al., Journal of Applied Physiology 110, 774–780 (2010)
  5. Japjec et al., Biomedicines 9(11), 19066–19077 (2021)
  6. Drmic et al., World Journal Gastroenterology 24(48), 5462–5476 (2018)
  7. Vukojević et al., Vascular Pharmacology 106, 54–66 (2018)
  8. Hsieh et al., Journal of Molecular Medicine 95(3), 323–333 (2017)
  9. Sikiric et al., PMCID: PMC6271067 (2018)
  10. Examine.com, BPC-157 Research Summary
  11. RupaHealth, Science-backed BPC-157 Guide
  12. Yoon et al., FASEB Journal 35, e22089 (2021)
  13. Lechner et al., Pharmaceutical Research 36, 111 (2019)
  14. Vazquez et al., Journal of Immunology 209, 194–203 (2022)
  15. Sokolowski et al., Science 346, 1166–1170 (2014)
  16. Ebrahim et al., Journal of Clinical Endocrinology and Metabolism 103, 2349–2358 (2018)
  17. Liu et al., Nature 560, 239–242 (2018)
  18. Chen et al., Cell Stem Cell 28, 137–150 (2021)
  19. He et al., Frontiers in Pharmacology 11, 306 (2020)
  20. Pezzoli et al., Nature Communications 11, 3698 (2020)
  21. Martin et al., Journal of Investigative Dermatology 138, 2429–2439 (2018)
  22. Grillo et al., Journal of Clinical Medicine 9, 344 (2020)
  23. Feng et al., Journal of Cell Science 132, jcs222376 (2019)
  24. Rasmussen et al., Pharmacological Research 118, 99–108 (2017)
  25. Bhoopathy et al., Regenerative Medicine 16, 53–69 (2021)
  • Lyophilized / Dry powder: Store at -20 °C (dark, desiccated); shelf life ~12 months.
  • Dissolved (aqueous): sterile water, 4 °C, use within 7 days.
  • Long-term: aliquot & -80 °C for up to 6 months; avoid > 2 freeze-thaw cycles.